Anicca: Impermanence
Every made thing keeps slipping away even while the hands still hold it. Read "vanity" by its older sense, a puff of vapor, and the years of careful wisdom, knowledge, and skill turn into breath fogged on a cold window: clear and solid for a moment, already thinning as you look. However clever the hands that raised it, nothing they build is given to stay, and the finest workmanship thins at the same rate as the clumsiest.
Maraṇasati: Mindfulness of death
Keep your own dying quietly in sight through the ordinary day. Leaving it waits for no plan of yours; one morning the breath simply stops, and the whole estate, the houses and vineyards and clever accounts, is set down at a door you step through with empty hands. Hold that plain door steadily in view and the frantic piling of more loosens its grip on you, hour by hour, on its own.
Anattā: Not-self
Nothing you gather is finally yours to keep, however hard you worked for it. That "portion" carries your name only the way a hotel room carries it for a night; the next guest, who never lifted a finger toward the cost, is already walking down the hall with the key. The stranger set to inherit only makes plain what was so the whole time, that the pile answered to no owner and never could.
Upādāna: Clinging
The suffering sits in the act of holding on. So much wisdom, knowledge, and skill were poured into the work that the fingers close hard around it, and the harder they close, the deeper the tear when it is finally pulled from them. Open the fingers a little now, while you still can, and there is far less to rip away when the pulling comes.
Dukkha: Unsatisfactoriness
A low ache runs under even the most skillful, well-built life. Feel "a great evil" as that ache itself: do every part of it well, labor with full wisdom, and the fruit still cannot fill you, because the ground keeps shifting under your feet. Poor workmanship was never the trouble; a shifting world holds no lasting rest, and turning from the chase toward what does not decay is where the road out quietly opens.